The San Francisco 49ers defeated the Miami Dolphins 35-13 on September 20, 2026, at Levi’s Stadium in Santa Clara, California, according to game records and reporting from the Associated Press. Capitalizing on touchdowns across their first five possessions, the 49ers improved to a 2-0 record on the season following their return from an international trip to Australia.
Purdy and Efficient Offense Ground the Dolphins
San Francisco quarterback Brock Purdy led the offensive charge in front of an announced attendance of 70,878. Purdy completed 20 of 22 pass attempts for 287 yards and two touchdowns, while also adding a 3-yard rushing score. The efficient outing allowed the home side to build an advantage before halftime and coast through the final quarters.
McCaffrey and Kittle Fuel First-Half Surge
Running back Christian McCaffrey anchored the ground game for the 49ers, punching in two short-yardage scores from the 1-yard line in the first and third quarters respectively. Tight end George Kittle contributed 80 receiving yards and a 12-yard touchdown catch, marking his scoring return following an injury absence. Kyle Juszczyk also hauled in a 6-yard touchdown pass from Purdy during the third-quarter surge.
Willis and Achane Find Limited Answers in Defeat
For Miami, the defeat drops the team to 0-2 for the young campaign. Quarterback Malik Willis entered the lineup and threw for 197 yards on 14-of-23 passing, connecting with wide receiver Ryan Miller for a late 77-yard touchdown in the fourth quarter. Running back De’Von Achane paced the Dolphins’ rushing attack with 74 yards on 20 carries, but the offense struggled to sustain drives against a disciplined San Francisco defense.
Special Teams and Defense Seal the Blowout
Special teams played a steady role for the 49ers as kicker Riley Patterson converted field goals from 28 and 24 yards out during the second quarter. However, the inability to stop the 49ers’ opening script proved decisive.
Tackles Pile Up as Week 2 Concludes
Defensively, the 49ers limited Miami to 284 total yards while registering 382 yards of their own. J. White notched a sack. Taaffe recorded nine tackles for the Dolphins.

The matchup marked the conclusion of the second week of action for both franchises. The San Francisco 49ers will look to extend their winning streak in Week 3, while the Miami Dolphins return to the drawing board to hunt for their first victory of the 2026 NFL season.