Mikel Arteta makes five changes to the starting XI from the side that faced Southampton on Thursday evening.
Maitland-Niles, David Luiz, Willock, Kolasinac and Lacazette are coming, instead of Bellerin, Holding, Ceballos, Aubameyang and Nketiah, all of whom are substitutes
Sheffield United: Henderson, Baldock, Stevens, Fleck, Basham, Lundstram, McBurnie, Egan, Norwood, McGoldrick, Robinson.
Sheffield United replaces: L. Freeman, Sharp, Jagielka, K. Freeman, Mousset, Osborn, Moore, Zivkovic, Montagne
Arsenal: Martinez, Mustafi, David Luiz, Tierney, Maitland-Niles, Xhaka, Willock, Kolasinac, Pepe, Lacazette, Saka
Substitutes for Arsenal: Macey, Bellerin, Sokratis, Holding, Smith, Caballos, Nelson, Nketiah, Aubameyang
Referee: Paul Tierney
assistants: Ian Hussin and Marc Perry
Fourth official: Robert Jones