Trent Williams and Dre Greenlaw Doubtful for 49Ers vs. Cowboys

San Francisco 49ers offensive tackle Trent Williams and linebacker Dre Greenlaw are listed as doubtful for Sunday’s game against the Dallas Cowboys after sustaining shoulder and knee injuries during Thursday’s practice, ESPN reported.

The San Francisco 49ers added two players to their injury report ahead of Sunday's matchup. Williams suffered a shoulder injury during Thursday’s session, while Greenlaw picked up a knee issue on the same day.

Williams Misses Practice While Greenlaw Remains Limited

Following Thursday’s setback, both players had limited participation in practice. Greenlaw returned for another limited session on Friday, but Williams did not practice at all.

“When you injure your shoulder on a Thursday, it’s not something that leaves you entirely calm,” 49ers head coach Kyle Shanahan told ESPN regarding Williams. “Sunday comes fast, but we hope that is enough time for him to be fine.”

If Williams cannot play, the Niners will turn to tackle Vederian Lowe to anchor the left side of the line. Should Greenlaw miss the contest, rookie Jaden Dugger is slated to fill the weak-side linebacker role.

“We expect to have Dre on Sunday; but if not, the next player will take his place, and so far, whoever is next in the rotation has proven their worth,” Shanahan told ESPN.

Mike Evans Remains Sidelined With Achilles Tendinitis

Wide receiver Mike Evans will miss his third game due to an Achilles tendon issue. He stands as the only player officially ruled out by San Francisco for the Dallas game as he recovers from tendinitis that flared up in Week 6 against the Washington Commanders.

Shanahan discussed the potential timeline for Evans on Friday afternoon, noting a possibility of a return next week against the Minnesota Vikings, though nothing is finalized. The organization is prioritizing long-term health over an early return.

“The recovery is on the right track,” Shanahan told ESPN. “I’m sure that if this were the last game of the season or something similar, he could play. But we want to make sure he heals completely to prevent the problem from recurring; either way, everything is moving in the right direction.”

Cornerbacks Face Doubt as Deebo Samuel Returns

Beyond Williams and Greenlaw, San Francisco lists three key cornerbacks—Deommodore Lenoir (foot), Renardo Green (back), and Upton Stout (shoulder/neck)—as doubtful to face the Cowboys. Defensive tackle C.J. West (knee) and safety Nate Hobbs (adductor) are working their way back from injured reserve and could be activated on Saturday.

On the positive side for the offense, wide receiver Deebo Samuel practiced all week and received clearance to return after missing time since Week 5 with a hamstring injury.

“He had a good week, he is healthy,” Shanahan told ESPN. “It’s his first week back, so he’s still readapting, but he took great care of himself while he was injured and has had a good week.”

The 49ers face the Dallas Cowboys on Sunday at Levi’s Stadium in Santa Clara, California, with kickoff scheduled for 5:20 p.m. local time (00:20 UTC).

Editor-in-Chief

Editor-in-Chief

Daniel Richardson is the Editor-in-Chief of Archysport, where he leads the editorial team and oversees all published content across nine sport verticals. With over 15 years in sports journalism, Daniel has reported from the FIFA World Cup, the Olympic Games, NFL Super Bowls, NBA Finals, and Grand Slam tennis tournaments. He previously served as Senior Sports Editor at Reuters and holds a Master's degree in Journalism from Columbia University. Recognized by the Sports Journalists' Association for excellence in reporting, Daniel is a member of the International Sports Press Association (AIPS). His editorial philosophy centers on accuracy, depth, and fair coverage — ensuring every story published on Archysport meets the highest standards of sports journalism.

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