NFL Week 4 brought significant injury concerns for several star players across the league, highlighted by a concussion sustained by Cincinnati Bengals wide receiver Ja’Marr Chase and a left ankle sprain for Lamar Jackson. Both players exited their respective games on Sunday, joining a growing casualty list that also featured Saquon Barkley, who left his contest against the Los Angeles Rams in the first quarter.
The developments leave multiple high-profile rosters facing critical evaluations and potential lineup adjustments as the season progresses. While teams work through official medical assessments, the immediate availability of several key offensive weapons remains uncertain heading into the next slate of games.
Ja’Marr Chase Evaluated for Concussion After Heavy Hit
Cincinnati Bengals wide receiver Ja’Marr Chase sustained a concussion during the second quarter of Sunday’s matchup against the Jacksonville Jaguars. The injury occurred with 12 minutes and 4 seconds remaining in the first half after Chase caught a pass from quarterback Joe Burrow at the Jaguars’ 29-yard line. As he was brought down, Jacksonville cornerback Jarrian Jones grabbed the grille of Chase’s helmet, followed by a heavy hit from linebacker Ventrell Miller. Chase appeared to strike his head against the turf. He remained on the ground for several minutes before leaving the field, and the team officially ruled him out at halftime.
Bengals said WR Ja’Marr Chase is being evaluated for a possible concussion.
— Adam Schefter (@AdamSchefter) October 4, 2026
Prior to his exit, Chase had recorded three touchdowns and 18 receptions for 185 receiving yards on the season. The wide receiver had not missed a game due to injury since 2023, making his status a major storyline for the Bengals’ offense.
Lamar Jackson Wears Protective Boot Following Ankle Sprain
Lamar Jackson suffered a left ankle sprain late in the first half of Sunday’s victory after being tackled. Tyler Huntley stepped in behind center to finish the game in Jackson’s absence. Jackson spent the remainder of the contest on the sidelines, visibly limping while shouting encouragement to his teammates.
Upon leaving the stadium, Jackson was wearing a protective boot, casting doubt on his availability for next week’s game against Atlanta. Coach Jesse Minter addressed the media regarding his condition after the final whistle. “I don’t know enough about his condition right now. We’ll have to see,” Minter stated.

League-Wide Injury Updates and Notable Performances
Injury Update: DJ Moore (shoulder) is questionable to return.
— Buffalo Bills PR (@BuffaloBillsPR) October 4, 2026
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