For Messi, however, it is only the latest record in an amazing career that shows no signs of slowing down.
The cheeky end was his 630th goal in 724 games for the Catalan club, combined with the 70 goals he scored on the international stage.
They are statistics that make him a comfortable goal scorer for both the club and the country.
The 33-year-old also joins an illustrious list of names like Pelé, Ferenc Puskas, and Gerd Muller to reach the 700 milestone, which includes his long-time rival Cristiano Ronaldo.
Barcelona slips again
Despite his groundbreaking performance, Messi was in no mood to celebrate.
His wonderfully stricken free kick was not enough to score all three points for his team, which seem to be neglected in defending the title.
The hosts threw the lead away twice, with Saul converting two penalties for third-placed Atletico.
Messi had been involved in the kick-off in Barcelona when his corner bounced off Diego Costa for an own goal.
However, the result leaves the Catalan point behind Real Madrid after playing an additional game.
“It’s a real shame and the championship looks a lot more difficult with every game,” said Barcelona coach Quique Setien after the game.
“If we drop these points in reality, we will move further away from the title, but we have to keep working hard.”