Hazard and Chelsea hold a slight advantage after a 1-1 draw in the first leg in Germany.
And their star forward could hand the Blues the perfect parting gift by helping them book a place in the final.
Hazard is expected to move to Real Madrid at the end of the season and the Spanish giants could announce the deal as soon as their season is over.
But for now, Hazard is set to line up in his usual spot on the left of a three-man attack, alongside Willian and Olivier Giroud, who is the competition’s top scorer with 10 goals this season.
While Hazard’s presence will be a huge boost to Maurizio Sarri’s side, they were dealt a huge blow in the weekend’s 3-0 win over Watford when N’Golo Kante limped off with a hamstring injury.
Mateo Kovacic is expected to come back into the team to line up with Ruben Loftus-Cheek and Jorginho in midfield.
At the back, Andreas Christensen is set to partner David Luiz in the heart of defence.
Emerson Palmieri and Cesar Azpilicueta will line up in the full-back positions.
Boss Sarri says Chelsea deserve to have something to show for his first season in charge.
Beating Watford secured Champions League football for next season and now he is now looking to win his first-ever piece of silverware as a manager.
“I am delighted at achieving the club’s target of making the top four,” the Italian said.
“We want to reach the Europa League final and win it because we deserve a trophy this season.
“It’s not easy because we have to play a dangerous team as we saw in the first leg.
“They’re dynamic and aggressive and when they can find spaces, it’s a dangerous match.
“In a semi-final you have to play against a strong team with very strong players. It’s difficult to be the favourite in a semi-final.”
Chelsea predicted line up to face Eintracht Frankfurt
Kepa; Azpilicueta, Luiz, Christensen, Emerson; Loftus-Cheek, Jorginho, Kovacic; Willian, Giroud, Hazard